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There in no cure for HCV, yet HCV untreated can kill you.
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| Self-medication of Interferon |
In the 1980's scientists discovered that interferon was some how able to produce
a transient response in HCV infected patients where the amount of HCV virus would
descend to nondetectable levels. Patients were treated just with interferon
injections seven times a week. Titled "Interferon Monotherapy" this
treatment eliminated HCV in 30% patients, yet when treatment stopped 50 percent
relapsed and showed signs again. Interferon Monotherapy was therefore roughly
only 15 percent effective.
In 1998, Scientists announced a new type of treatment called "Combination
Therapy." This was simply the intake of the antiviral medication
"Ribavirin" with fewer doses of interferon. Today, Combination
Treatment is the typical treatment given to HCV infected patients. Patients
must take 1000-1200mg of Ribavirin orally and inject three million units
or nine micrograms of interferon 4 times a week. With the addition of
Ribaviran to the treatment, HCV is lowered to undetectable levels in 35-45
percent of patients. Unfortunately, the cost for this treatment is roughly
5000 dollars per six months excluding monitoring costs. If this treatment is
stopped, HCV relapse will occur.
Patients with acute HCV have a much greater chance of showing
a response to either Interferon Monotherapy or Combination Therapy. Treatment on
chronic HCV patients may not yield results. This makes the need to diagnose
HCV early imperative, yet the long incubation period of HCV makes this
a very hard task to complete.
Scientists still have no idea how inteferon affects or suppresses HCV.
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